TREATMENT OF LUMBAR INTERVERTEBRAL DISC LESIONS BY DIRECT INJECTION OF CHYMOPAPAIN

Treatment of lumbar intervertebral disc lesions by direct injection of chymopapain.

Chymopapain is an enzyme that has the ability to disrupt the mucopolysaccharide-protein complex of an intervertebral disc. It has no apparent effect upon the collagen of the intervertebral disc, of the longitudinal ligaments, or of the dura mater, nor does it have any effect on the lipid of nerve tissue. No deleterious effects have been seen in animals after intrathecal or epidural injection of...

incidence of microscopic lumbar intervertebral disc calcification and its correlation to endplate degeneration type and disc histopathologic angiogensis

چکیده ندارد.

Treatment of lumbar intervertebral disc prolapse.

Intervertebral disk-space infection after chymopapain injection.

Four patients who had received chymopapain injections for treatment of herniated lumbar disks were evaluated by computed tomography (CT) because of persistent low back pain and suspicion of infection. Irregularity of the vertebral end-plate and a mottled appearance of the vertebral bodies suggested the diagnosis of disk-space infection in all four cases. CT-guided biopsy of the disk space was p...

Treatment of lumbar intervertebral disc protrusions by manipulation.

From 1975 through 1983, a total of 517 patients with protruded lumbar discs were admitted for manipulative treatment. Of these, 76.8% had satisfactory results. There were 73 recurrences (14.1%) at intervals ranging from two months to 12 years. Forty-seven cases did not respond to manipulation. These results indicate that manipulation of the spine can be effective treatment for lumbar disc protr...